Cognition, Flavonoids, Exercise, Gut Microbiome
Age-related Cognitive Changes: Effects of Combined Flavonoid Intake and Physical Exertion Mediated by the Gut Microbiome
Appalachian State University
240 participants
Jan 1, 2025
INTERVENTIONAL
Conditions
Summary
This NIH project will examine the effects of routine flavonoid-rich blueberry intake (12-weeks), combined with or in the absence of regular moderate exercise, on cognitive function in a clinical population of older participants identified as experiencing age-related cognitive changes. This project's hypothesis is that the combination of flavonoid-rich diet and routine physical activity may potentiate cognitive benefits and reduce cognitive decline in an aging population, via mechanisms mediated by the gut microbiome.
Eligibility
Plain Language Summary
Simplified for easier understanding
This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.
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Interventions
50 g/d blueberry powder supplement
Five 45-min walking sessions per week
50 g/d placebo powder supplement
Five 45-min stretching sessions per week
Locations(1)
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NCT06495190