Impact of Estimated Concentration of Propofol on Implicit Memory Formation
Impact of Target Controlled Infusion Estimated Concentration of Propofol on Implicit Memory Formation During Propofol-Remifentanil General Anaesthesia
University of Padova
80 participants
Jul 1, 2024
OBSERVATIONAL
Conditions
Summary
Implicit memory formation and learning during general anaesthesia is a still debated question and no anesthetic regimen (ie intravenous anaesthesia vs inhalatory one) nor analgesic regimen (i.e. low or high opioids usage) has been identified for prevention. With this study the investigators aim to investigate if, during Total Intravenous Anaesthesia with Target Controlled Infusion (TIVA-TCI) different concentrations of Propofol at loss of responsiveness, maintenance and return of responsiveness can have a role in implicit memory formation.
Eligibility
Inclusion Criteria1
- General anaesthesia with TIVA-TCI
Exclusion Criteria3
- ASA > III
- Benzodiazepines premedication
- Neurological/Psychiatric disease
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Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06497855