RecruitingNCT06497855

Impact of Estimated Concentration of Propofol on Implicit Memory Formation

Impact of Target Controlled Infusion Estimated Concentration of Propofol on Implicit Memory Formation During Propofol-Remifentanil General Anaesthesia


Sponsor

University of Padova

Enrollment

80 participants

Start Date

Jul 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Implicit memory formation and learning during general anaesthesia is a still debated question and no anesthetic regimen (ie intravenous anaesthesia vs inhalatory one) nor analgesic regimen (i.e. low or high opioids usage) has been identified for prevention. With this study the investigators aim to investigate if, during Total Intravenous Anaesthesia with Target Controlled Infusion (TIVA-TCI) different concentrations of Propofol at loss of responsiveness, maintenance and return of responsiveness can have a role in implicit memory formation.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 90 Years

Inclusion Criteria1

  • General anaesthesia with TIVA-TCI

Exclusion Criteria3

  • ASA > III
  • Benzodiazepines premedication
  • Neurological/Psychiatric disease

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Locations(1)

Treviso Regional Hospital

Treviso, TV, Italy

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NCT06497855


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