RecruitingNCT06499714
HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle Phase
HighCycle Study: Effect of High Altitude on Acute Mountain Sickness in Women Related to Their Menstrual Cycle Phase: A Prospective Cohort Study at 3600 m
Sponsor
University of Zurich
Enrollment
90 participants
Start Date
Jul 15, 2024
Study Type
OBSERVATIONAL
Summary
Prospective cohort study investigating the menstrual cycle phase (MCP)-dependent incidence of acute mountain sickness (AMS) in women travelling to 3600 m.
Eligibility
Sex: FEMALEMin Age: 18 YearsMax Age: 44 Years
Inclusion Criteria5
- Healthy, non-smoking women, age 18-44 years, without any disease and need of regular medication (including oral contraceptives).
- BMI >18 kg/m2 and <30 kg/m2
- Born, raised and currently living at altitudes <1000 m
- Written informed consent
- Premenopausal, eumenorrheic cycle
Exclusion Criteria5
- Other types of contraceptives (hormonal intrauterine device, vaginal ring, subcutaneous injections or implants, among others)
- Pregnancy or nursing
- Anaemic (haemoglobin concentration <10g/dl)
- Any altitude trip <4 weks before the study
- Allergy to acetazolamide and other sulfonamides
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Interventions
OTHERExposure to 3600 m
Participants will travel to and stay for 2 days at an altitude of 3600 m.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06499714