RecruitingNot ApplicableNCT06500975

Long Term Outcomes After Vestibular Implantation


Sponsor

Johns Hopkins University

Enrollment

32 participants

Start Date

Dec 1, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Although cochlear implants can restore hearing to individuals who have lost cochlear hair cell function, there is no widely available, adequately effective treatment for individuals suffering chronic imbalance, postural instability and unsteady vision due to bilateral vestibular hypofunction. Prior research focused on ototoxic cases has demonstrated that electrical stimulation of the vestibular nerve via a chronically implanted multichannel vestibular implant can partially restore vestibular reflexes that normally maintain steady posture and vision; improve performance on objective measures of postural stability and gait; and improve patient-reported disability and health-related quality of life. This single-arm open-label study extends that research to evaluate outcomes for up to 8 individuals with non-ototoxic bilateral vestibular hypofunction, yielding a total of fifteen adults (age 22-90 years at time of enrollment) divided as equally as possible between ototoxic and non-ototoxic cases.


Eligibility

Min Age: 22 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying Labyrinth Devices MVI™ Multichannel Vestibular Implant System for people with aminoglycoside toxicity, bilateral vestibular deficiency, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include aged 22 Years to 90 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DEVICELabyrinth Devices MVI™ Multichannel Vestibular Implant System

Continuously motion-modulated stimulation delivered by a vestibular implant already implanted under a prior study protocol (Labyrinth Devices MVI™ Multichannel Vestibular Implant System)


Locations(1)

Johns Hopkins School of Medicine

Baltimore, Maryland, United States

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NCT06500975


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