Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy

This study compares two pain-relief medications — dexamethasone and magnesium — added to a local anesthetic nerve block (called an erector spinae plane block) to control pain after kidney removal surgery (nephrectomy). It aims to find which addition works better. **You may be eligible if...** - You are an adult between 18 and 65 years old - You are scheduled to have one kidney removed (unilateral nephrectomy) - Your physical health status is classified as ASA II or III (moderate health risks) **You may NOT be eligible if...** - You refuse participation - You are under 18 - You are allergic to any of the medications used in the study - Your surgical incision will run down the middle of the abdomen (midline incision) - You are having both kidneys removed - You have a deformed or unusual spine anatomy (such as kyphoscoliosis) - You have a known nerve or psychiatric disorder, or chronic pain condition - You have a local infection at the injection site - You are in an unstable medical state (hemodynamic instability) Talk to your doctor to see if this trial is right for you.