Dexamethasone Versus Mg Added to Bupivacaine Used in ESPB for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
The Efficacy of Dexamethasone Versus Magnesium Sulphate Added to Bupivacaine Used in Erector Spinae Plane Block for Perioperative Pain Control in Patients Undergoing Unilateral Nephrectomy
National Cancer Institute, Egypt
78 participants
May 1, 2024
INTERVENTIONAL
Conditions
Summary
Aim of the study: The current study aims to compare the effect of adding dexamethasone versus magnesium sulfate to bupivacaine in ultrasound-guided erector spinae plane block on the severity of postoperative pain. Primary Objectives: \- To compare the effect of ESPB without additives to the effect of adding dexamethasone and to the impact of adding magnesium sulfate in the form of post-operative morphine consumption
Eligibility
Inclusion Criteria3
- Adult (18 - 65)
- Patients undergoing unilateral nephrectomy
- ASA II / III
Exclusion Criteria9
- Patient refusal
- Age less than 18 years
- Allergy to any of the studied medications
- Mid line incision
- Bilateral nephrectomy
- Distorted anatomy of the back (e.g. kyphoscoliosis)
- Known neurologic disorders, psychiatric disorder or chronic pain
- Local infection
- Hemodynamic instability
Interventions
ESP block will be performed U/S at the level of T 10 paraspinal level. The ultrasound transducer should be placed in the midline of the back at the desired level. The probe should then slowly be moved laterally until the transverse process is visible. The transverse process requires differentiation from the rib at that level. Erector spinae muscle should be identified superficial to the transverse process. The needle inserted superior to the ultrasound probe in the cephalad to caudal direction. Once the needle tip is below the erector spinae muscle. This separation from the transverse process confirms the proper needlemposition. The local anesthetic should then be injected in 5 ml increments. The block will be performed preoperatively.
Locations(1)
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NCT06501079