The Renal Protective Effects of Remote Ischemic Preconditioning in Patients With Chronic Kidney Disease

This study tests whether remote ischemic preconditioning (RIC) — a technique where a blood pressure cuff is briefly inflated and deflated on the arm in cycles — can help protect the kidneys and slow the progression of chronic kidney disease (CKD). **You may be eligible if...** - You have chronic kidney disease with a kidney function (eGFR) of at least 15 mL/min/1.73m² - You are 18 or older - Your daily urine protein is 3.5 g or less - You have signed the informed consent form **You may NOT be eligible if...** - You have nephrotic syndrome (very high protein in urine with swelling) - You have acute kidney injury - You have already received kidney replacement therapy (dialysis or transplant) - You have diabetes or your HbA1c (blood sugar control marker) is above 8% - You have very high cholesterol with high LDL - You have injuries, infections, or blood vessel problems in both arms that prevent using the blood pressure cuff - You have a blood clotting disorder, history of serious bleeding, or low platelets - You have atrial fibrillation, severe heart conditions, or recent heart attack - You are pregnant or breastfeeding Talk to your doctor to see if this trial is right for you.