RecruitingNCT06503848

Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (MAMBO) Phase I

Migraine Attack Treatment Response Molecular and Clinical BiOmarkers (The MAMBO Study) Phase I


Sponsor

Hospital Universitari Vall d'Hebron Research Institute

Enrollment

108 participants

Start Date

Jan 25, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to identify differential traits in spontaneous migraine attacks that can help us predict the response to treatment with sumatriptan. Participants will be asked to register the headache characteristics before and after taking sumatriptan and whether the treatment was effective or not during four migraine attacks.


Eligibility

Min Age: 18 YearsMax Age: 45 Years

Inclusion Criteria5

  • Migraine with or without aura diagnosis according to ICHD-3 criteria
  • \<8 migraine days per month
  • Be able to read, write and understand instructions.
  • Have internet access and mail address
  • Signing of the informed consent

Exclusion Criteria7

  • Active preventive treatment for migraine
  • Active medication with an effect over the central nervous system
  • Serious physical or psychiatric condition
  • Cardiovascular or hepatic disease
  • Pregnant or breastfeeding women
  • Any triptan contraindication
  • Severe migraine attacks without previous response to triptans or NSAIDs

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Interventions

DRUGSumatriptan

Register the response to treatment and headache characteristics.


Locations(1)

Hospital Universitari Vall d'Hebron

Barcelona, Spain

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NCT06503848


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