RecruitingPhase 2NCT06505187

Celecoxib for ENT Pain Management

Celecoxib Pain Management Following Superficial Parotidectomy: Opioid Sparing Protocol


Sponsor

University of Wisconsin, Madison

Enrollment

84 participants

Start Date

Feb 28, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to find out whether pain can be managed after an operation with celecoxib instead of oxycodone. The main question it aims to answer is if use of celecoxib plus Tylenol reduces the need for oxycodone. Researchers will compare the combination of celecoxib and Tylenol to a placebo to find out whether celecoxib works to manage pain. Participants will: * Take celecoxib, or a placebo, plus Tylenol with opioids as needed * Keep a diary of their pain between visits * Complete questionnaires


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Celecoxib, a drug called Oxycodone, and others for people with parotidectomy. The study is currently recruiting participants at 1 location.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGCelecoxib

200mg every 12 hours

DRUGTylenol

650mg q6h

DRUGOxycodone

5mg every 6 hours as needed

DRUGplacebo

every 12 hours


Locations(1)

University of Wisconsin

Madison, Wisconsin, United States

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NCT06505187


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