RecruitingNot ApplicableNCT06506513

Targeting the Skeletal Muscle to Treat Metabolic Dysfunction-associated Steatotic Liver Disease

Targeting Myosteatosis Though Physical Exercise to Treat Metabolic Dysfunction-associated Steatotic Liver Disease


Sponsor

Cliniques universitaires Saint-Luc- Université Catholique de Louvain

Enrollment

60 participants

Start Date

Sep 1, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

Muscle changes including myosteatosis are reported as highly prevalent in metabolic dysfunction-associated steatotic liver disease (MASLD). Recent studies highlighted a link between muscle fat content and liver disease severity. Conversely, MASLD histological remission though diet or metabolic surgeries is also linked to a decrease in muscle fat content. Therefore, skeletal muscle appears as a potential target to treat MASLD.


Eligibility

Min Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying High-intensity interval training, Low intensity exercise training, and others for people with metabolic dysfunction-associated steatotic liver disease. The study is currently recruiting participants at 2 locations. People eligible for this study include aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERHigh-intensity interval training

High-intensity interval training

OTHERModerate intensity exercise training

Moderate intensity exercise training

OTHERLow intensity exercise training

Low intensity exercise training


Locations(2)

Cliniques universitaires Saint-Luc

Brussels, Belgium

Centre d'investigation clinique en nutrition

Louvain-la-Neuve, Belgium

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NCT06506513


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