RecruitingNCT06508502

Pancreatitis - Microbiome as Predictor of Severity II


Sponsor

University Medical Center Goettingen

Enrollment

700 participants

Start Date

May 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this observational study is to evaluate the orointestinal microbiome and microbial derived metabolome in patients suffering from acute pancreatitis as a biomarker for severity. The main questions it aims to answer are: * Can the orointestinal microbiome robustly predict the course of acute pancreatitis? * How does the microbiome impact the severity of an acute pancreatitis? Buccal/ rectal swabs, plasma and stool is collected from patients with acute pancreatitis within 48h after hospital admission.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Patients with initial diagnosis (\< 48h) of acute pancreatitis
  • Age ≥ 18 years
  • Patients able to understand/ give their written consent

Exclusion Criteria3

  • Recurrent acute pancreatitis (\>2 previous episodes)
  • Clinical or imaging signs of chronic pancreatitis
  • Referred patients with length of hospital stay \> 48h

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Locations(1)

University Medical Center Goettingen

Göttingen, Lower Saxony, Germany

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NCT06508502


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