RecruitingPhase 4NCT06513208
Ketorolac Effects on Post-operative Pain and Lumbar Fusion
Ketorolac Effects on Post-operative Pain and Lumbar Fusion: a Double Blind Randomized Controlled Trial
Sponsor
University of Maryland St. Joseph Medical Center
Enrollment
140 participants
Start Date
Jan 1, 2026
Study Type
INTERVENTIONAL
Conditions
Summary
A double blind prospective randomized trial of IV ketorolac vs. placebo in management of patients undergoing lumbar one or two level spinal fusions.
Eligibility
Min Age: 18 YearsMax Age: 85 Years
Inclusion Criteria5
- years old (inclusive)
- Elective posterior lumbar instrumented fusion
- One or two level fusion
- Consent to participate in study and willing to adhere to study follow up
- English proficiency
Exclusion Criteria9
- \< 18 or \> 85 years old
- History of renal failure, dialysis, or creatinine over 1.50 mg/dl
- Active or recent smoker (active within past 6 months)
- Revision surgery
- Auto/worker compensation
- Active cancer or history of chemotherapy in past 6 months
- Active narcotic use within 3 months of surgery date
- Infection at operative levels
- Any allergies to NSAIDs or Opioids
Interested in this trial?
Get notified about updates and connect with the research team.
Interventions
DRUGKetorolac Tromethamine
IV Ketorolac 15mg every 6 hours, x 4 doses
DRUGPlacebo
IV saline as placebo
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06513208