RecruitingEarly Phase 1NCT06520982

Early Neurovascular Adaptations in Aging Women


Sponsor

University of Missouri-Columbia

Enrollment

64 participants

Start Date

Sep 20, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Our goal is to enhance our understanding of early vascular adaptations in aging women with an emphasis on the sympathetic nervous system.


Eligibility

Sex: FEMALEMin Age: 18 YearsMax Age: 70 Years

Plain Language Summary

Simplified for easier understanding

This clinical trial is studying a drug called Acetylcholine, a drug called Estrogen, and others for people with aging, blood flow, and other related conditions. The study is currently recruiting participants at 1 location. People eligible for this study include women aged 18 Years to 70 Years.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGNorepinephrine

Infused intra-arterially in a dose-response fashion

DRUGIsoproterenol

Infused intra-arterially in a dose-response fashion

DRUGAcetylcholine

Infused intra-arterially in a dose-response fashion

DRUGNitroprusside

Infused intra-arterially in a dose-response fashion

DRUGEstrogen

Infused intra-arterially


Locations(1)

University of Missouri-Columbia

Columbia, Missouri, United States

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NCT06520982


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