RecruitingPhase 2NCT06522828

A Study to Evaluate SSGJ-707 in Advanced Gynecologic Cancer Patients

A Phase 2 Study to Evaluate the Safety and Efficacy of SSGJ-707 in Advanced Gynecologic Cancer Patients


Sponsor

Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd.

Enrollment

80 participants

Start Date

Oct 10, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This is an open, multicenter Phase II clinical study of SSGJ-707 combined with chemotherapy in the treatment of advanced/recurrent endometrial cancer and platinum-resistant ovarian cancer. The objective is to evaluate the safety, tolerability and antitumor activity of SSGJ-707 in the treatment of advanced/recurrent endometrial cancer and platinum-resistant ovarian cancer.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This trial is testing the safety and effectiveness of an experimental drug called SSGJ-707 in women with advanced endometrial cancer or platinum-resistant ovarian cancer. **You may be eligible if...** - You are between 18 and 75 years old - You have advanced endometrial cancer, OR ovarian cancer that has stopped responding to platinum-based chemotherapy - You are in good general health (ECOG 0 or 1) - Your expected survival is at least 12 weeks - You have signed informed consent **You may NOT be eligible if...** - You have active or uncontrolled brain metastases - You have unresolved side effects (grade 2 or higher) from prior cancer treatment (except hair loss or fatigue) - Your organ or bone marrow function is not adequate - You are pregnant or breastfeeding - You have a known allergy or intolerance to SSGJ-707 Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGSSGJ-707

SSGJ-707 is a bispecific antibody against human PD-1 and VEGF

DRUGcarboplatin

chemotherapy

DRUGpaclitaxel

chemotherapy


Locations(1)

Chongqing Cancer Hospital

Chongqing, China

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NCT06522828