RecruitingNCT06523543

Ultra-early Identification of Fetal Chromosomal Characteristics From Extravillous-trophoblast Cells


Sponsor

University Hospital, Montpellier

Enrollment

25 participants

Start Date

Nov 19, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

Demonstrate the efficacy of an ultra-early, non-invasive prenatal diagnostic method adaptable to various genetic indications to detect fetal chromosomal abnormalities.


Eligibility

Sex: FEMALEMin Age: 18 Years

Inclusion Criteria10

  • Pregnant woman
  • Singleton pregnancy
  • Pregnancy between 7 and 16 weeks of amenorrhea (WA)
  • Woman ≥ 18 years
  • Woman who has signed an informed consent
  • Woman affiliated to social security or equivalent scheme
  • Exclusions Criteria:
  • Person under guardianship or curatorship
  • Person placed under legal protection
  • Person unable to provide the participant with informed consent.

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Interventions

PROCEDUREInclusion (Visit 1 - Week 7-16)

Extraction of cervico-vaginal sampling

DIAGNOSTIC_TESTSecond semester of pregnancy (Visit 2 - Week 20-24)

Ultrasound examination (determination of chromosomal sex)

DIAGNOSTIC_TESTThird semester of pregnancy (Visit 3- Week 34)

Ultrasound examination (determination of chromosomal sex) if this has not be done during the Visit 2 or if a new determination correcting the previous one is provided.


Locations(1)

CHU de Montpellier

Montpellier, France, France

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NCT06523543


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