RecruitingNCT06523738

Left Atrial Volume Changes Who Underwent Cardioversion and Recurrence of AF After RF Ablation in Persistent AF (SAFE-AF)

Association of Left Atrial Volume Changes After Cardioversion and Recurrence of Atrial Fibrillation After Radiofrequency Ablation in Patients With Persistent Atrial Fibrillation


Sponsor

The Second Affiliated Hospital of Chongqing Medical University

Enrollment

100 participants

Start Date

Jul 1, 2019

Study Type

OBSERVATIONAL

Conditions

Summary

Electrical/pharmacological cardioversion improves structural remodeling of left atrium. We hypothesize that persistent atrial fibrillation (AF) patients with more significant left atrial size reduction after cardioversion have lower AF recurrence rates following radiofrequency ablation. The aim is to evaluate the relationship between changes in left atrial size 3 to 6 months after cardioversion and the recurrence rate of atrial fibrillation following radiofrequency ablation.


Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is examining whether changes in the size of the left atrium (an upper chamber of the heart) after cardioversion — a procedure that restores normal heart rhythm — can predict who will have their irregular heartbeat (atrial fibrillation, or AFib) return after a radiofrequency ablation procedure. The goal is to identify better markers to guide treatment decisions. **You may be eligible if...** - You have a confirmed diagnosis of persistent atrial fibrillation (AFib lasting more than 7 days but less than 6 months) - Your left atrium measured between 40 and 50 mm before cardioversion - You had a successful cardioversion (either with medication or electrical shock) to restore normal rhythm - You had at least two echocardiograms (heart ultrasounds) before and 3–6 months after cardioversion - You have provided informed consent **You may NOT be eligible if...** - You have previously had radiofrequency ablation for AFib - You have had prior cardiac surgery - You have cognitive impairment that prevents you from giving informed consent Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TEST1. electrical/pharmacological cardioversion. 2.pulmonary vein isolation

1\. electrical/pharmacological cardioversion. 2. pulmonary vein isolation for persistent atrial fibrillation


Locations(1)

The Second Affiliated Hospital of Chongqing Medical University

Chongqing, Chongqing Municipality, China

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NCT06523738