RecruitingNot ApplicableNCT06525402

Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy

The Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on The Degree of Oral Mucositis in Children Receiving Chemotherapy: A Randomized Controlled Trial


Sponsor

Burdur Mehmet Akif Ersoy University

Enrollment

54 participants

Start Date

Jan 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study was planned as a randomized controlled experimental study in order to compare the effects of oral care with saline and black mulberry syrup in addition to sodium bicarbonate on oral mucositis level in children aged 6-18 years receiving chemotherapy.


Eligibility

Min Age: 6 YearsMax Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is testing three different mouth rinse solutions — sodium bicarbonate (baking soda), saline (salt water), and black mulberry syrup — to see which is most effective at preventing or reducing oral mucositis (painful mouth sores) in children receiving chemotherapy. Mouth sores are a common and painful side effect of cancer treatment in children. **You may be eligible if...** - You are a child between 6 and 18 years old - You are currently receiving chemotherapy and are hospitalized for treatment - You are able to eat and drink normally (fed orally) - Both you and your parent or guardian are willing to participate and provide written consent **You may NOT be eligible if...** - You already have mouth sores at the start of the study - You have diabetes - You are receiving radiation therapy - You have recently had mouth or jaw surgery - You are receiving steroid therapy during chemotherapy - You are already using another mouth care product not part of this study Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERSodium Bicarbonate Group (Usual care)

In the clinic where the research was conducted, a guideline is routinely applied for the care of oral mucositis in line with the stages of oral mucositis. Sodium bicarbonate is used in line with this guideline. The first group, the control group, will receive routine oral care in the clinic with sodium bicarbonate. Oral care will be applied 4 times a day for 14 days.

OTHERSaline Group

The second group, the experimental group, will first receive oral care routinely applied in the clinic. Then, oral care will be given in the form of 5 ml mouthwash with saline. Oral care will be applied 4 times a day for 14 days.

OTHERBlack Mulberry Syrup Group

The third group, the experimental group, will first receive oral care routinely applied in the clinic. Then black mulberry syrup will be applied. Then, oral care will be given in the form of 5 ml mouthwash with black mulberry syrup. Oral care will be applied 4 times a day for 14 days.


Locations(1)

Isparta City Hospital

Isparta, Turkey (Türkiye)

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NCT06525402


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