RecruitingNot ApplicableNCT06525402

Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on Degree of Oral Mucositis in Children Receiving Chemotherapy

The Effect of Sodium Bicarbonate, Saline and Black Mulberry Syrup on The Degree of Oral Mucositis in Children Receiving Chemotherapy: A Randomized Controlled Trial


Sponsor

Burdur Mehmet Akif Ersoy University

Enrollment

54 participants

Start Date

Jan 30, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

This study was planned as a randomized controlled experimental study in order to compare the effects of oral care with saline and black mulberry syrup in addition to sodium bicarbonate on oral mucositis level in children aged 6-18 years receiving chemotherapy.


Eligibility

Min Age: 6 YearsMax Age: 18 Years

Inclusion Criteria5

  • The willingness of the family and the child to participate in the study
  • Parent and child have separately informed written consent form
  • Be between 6-18 years old
  • Receiving chemotherapy and being hospitalized for chemotherapy treatment
  • Being fed orally

Exclusion Criteria6

  • Oral mucositis in the first intraoral evaluation
  • Having diabetes
  • Receiving radiotherapy
  • Having a surgical procedure in the mouth and jaw area
  • Receiving steroid therapy during chemotherapy treatment
  • Using a method other than the methods used in the study to protect the oral mucous membrane throughout the study

Interventions

OTHERSodium Bicarbonate Group (Usual care)

In the clinic where the research was conducted, a guideline is routinely applied for the care of oral mucositis in line with the stages of oral mucositis. Sodium bicarbonate is used in line with this guideline. The first group, the control group, will receive routine oral care in the clinic with sodium bicarbonate. Oral care will be applied 4 times a day for 14 days.

OTHERSaline Group

The second group, the experimental group, will first receive oral care routinely applied in the clinic. Then, oral care will be given in the form of 5 ml mouthwash with saline. Oral care will be applied 4 times a day for 14 days.

OTHERBlack Mulberry Syrup Group

The third group, the experimental group, will first receive oral care routinely applied in the clinic. Then black mulberry syrup will be applied. Then, oral care will be given in the form of 5 ml mouthwash with black mulberry syrup. Oral care will be applied 4 times a day for 14 days.


Locations(1)

Isparta City Hospital

Isparta, Turkey (Türkiye)

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NCT06525402


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