RecruitingNCT06527157

Investigations of Reproductive Cancers in Women

PROspective ACcrual To Investigate reprOductive Cancers in womeN


Sponsor

PinkDx, Inc.

Enrollment

4,500 participants

Start Date

Jul 30, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The goal of this study is to create a non-invasive diagnostic test to rule out gynecological cancer in females aged 45 and older with abnormal uterine or postmenopausal bleeding.


Eligibility

Sex: FEMALEMin Age: 45 YearsMax Age: 100 Years

Inclusion Criteria6

  • Evidence of a personally signed and dated informed consent form indicating that the subject has been informed of all pertinent aspects of the study.
  • Willing and able to comply with scheduled visits, study plan, and other procedures.
  • Expected to be available for the duration of the study and can be contacted by telephone during study participation.
  • Females aged 45 and older (with roughly 80% of enrolled subjects over the age of 50).
  • Presence of uterus.
  • AUB or PMB being worked up to diagnose the cause of the bleeding

Exclusion Criteria8

  • Investigator site staff members directly involved in the conduct of the study and their family members or subjects who are PinkDx, Inc. employees or their family members.
  • Other medical or psychiatric conditions that would increase the risk of study participation in the judgement of the Investigator.
  • Women who have had a hysterectomy.
  • Women with a known history of endometrial cancer or uterine sarcoma.
  • Women who have received prior treatment for endometrial cancer.
  • Inability or unwillingness to sign informed consent.
  • Clinical suspicion of pregnancy.
  • Women who have used a tampon within 7 days of sample collection.

Locations(16)

University of Alabama, Birmingham

Birmingham, Alabama, United States

Sutter Health

Redwood City, California, United States

Advent Health Orlando

Orlando, Florida, United States

Ob-Gyne Associates of Lake Forest, Ltd

Lake Forest, Illinois, United States

Indiana University, Eskenazi Health

Indianapolis, Indiana, United States

Mayo Clinic

Rochester, Minnesota, United States

Washington University School of Medicine

St Louis, Missouri, United States

Columbia University

New York, New York, United States

Summa Health

Akron, Ohio, United States

The Ohio State University

Columbus, Ohio, United States

Avera Research Institute

Sioux Falls, South Dakota, United States

University of Tennessee Health Science Center

Memphis, Tennessee, United States

Meharry Medical College

Nashville, Tennessee, United States

Baylor College of Medicine/Texas Children's Hospital

Houston, Texas, United States

Houston Methodist

Houston, Texas, United States

University of Texas Health Science Center at San Antonio

San Antonio, Texas, United States

View Full Details on ClinicalTrials.gov

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NCT06527157


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