RecruitingNot ApplicableNCT06528184

Evaluating the Impact of Different Methods of HPV DNA Testing for Cervical Cancer Screening in Primary Care Settings

Sponsor

National Healthcare Group Polyclinics

Enrollment

650 participants

Start Date

Aug 5, 2024

Study Type

INTERVENTIONAL

Conditions

Uterine Cervical Neoplasms

Summary

Primary objective of the study is to determine the extent that offering of self-sampling in addition to clinician-sampling Human Papillomavirus (HPV) DNA testing will increase detection of HPV DNA through an increase in uptake rates of cervical cancer screening as compared to offering clinician-sampling HPV DNA testing alone. The hypothesis is that offering additional self-sampling will increase the detection of high-risk HPV DNA by at least 7.7%.

Eligibility

Sex: FEMALEMin Age: 30 YearsMax Age: 69 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing different methods of HPV DNA testing (a test used to detect the virus that can cause cervical cancer) to see which is most effective for cervical cancer screening in regular clinic settings in Singapore. **You may be eligible if...** - You are a female Singapore citizen between 30 and 69 years old - You are due for cervical cancer screening - You have had sexual intercourse before - You can read and communicate in English, Chinese, or Malay - You are able to give informed consent **You may NOT be eligible if...** - You have never had sexual intercourse - You are currently pregnant - You have a history of cervical cancer or have had your cervix removed - You are unable to communicate in the listed languages Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DIAGNOSTIC_TESTSelf-sampled HPV DNA testing

Participants will be offered HPV DNA testing done through self-sampling (using self-sampling HPV DNA kits to obtain a mid-vaginal swab)

DIAGNOSTIC_TESTClinician-sampled HPV DNA test

Participants will be offered HPV DNA testing through clinician sampling (clinician-sampling (speculum examination by a nurse to obtain a cervical swab)