Surgery Plus Reduced Target Chemoradiotherapy vs Surgery Plus Reduced Dose Chemoradiotherapy for Newly Diagnosed Operable Nasopharyngeal Carcinoma.

This study is comparing two approaches for treating newly diagnosed, operable nasopharyngeal carcinoma (cancer at the back of the nose and throat): one using radiation aimed at a smaller target area, and another using a lower total radiation dose. Both are combined with chemotherapy and surgery. **You may be eligible if...** - You have been diagnosed with nasopharyngeal carcinoma (confirmed by biopsy) - Your cancer is operable (the tumor can be surgically removed) - Your overall health is good (performance score 0–1) - You have a specific cancer subtype (WHO type II or III) **You may NOT be eligible if...** - Your cancer cannot be surgically removed - You are in poor overall health - You have a different histological type not covered by the study - You have other serious medical conditions Talk to your doctor to see if this trial is right for you.