RecruitingNot ApplicableNCT06533137

"How Awareness and Subjectivity Modulate the Placebo Effect"

Evaluating the Impact of Perceived Control on Placebo Effectiveness: A Comparison Between Classic and Self-Administered Placebo Paradigms


Sponsor

Fondazione Don Carlo Gnocchi Onlus

Enrollment

84 participants

Start Date

Nov 28, 2022

Study Type

INTERVENTIONAL

Conditions

Summary

This study consists of a three-group experimental design (active placebo, passive placebo, control) with the primary outcome being perceived fatigue during a cycle ergometer training session. A pre-intervention assessment is planned, in which participants complete (online, via Qualtrics) the Borg Rating of Perceived Exertion (Borg CR10 Scale) and the Positive and Negative Affect Schedule (PANAS; scale for assessing positive and negative emotions). During the intervention, which consists of a cycle ergometer session with 10 minutes of warm-up and 10 minutes of more intense activity, participants will wear a heart rate monitor (Garmin HRM-Pro) to record heart rate and respiratory rate. In addition to these outcomes, distance traveled and speed achieved, extracted from the cycle ergometer data, will also be considered. At the end of the session, the pre-intervention assessment (Borg CR10 and PANAS) will be repeated, and a perceived control scale (Locus of Control of Behaviour) will also be administered.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • People who have a sports medical certificate
  • People who speak Italian
  • People who give their informed consent

Exclusion Criteria3

  • People who do not have a sports medical certificate
  • People who do not speak Italian
  • People who do not give their informed consent

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Interventions

OTHERNeutral ginger-flavored drink described as energizing, hypoglycemic, caffeine-based drink

It is a neutral ginger-flavored drink with no energizing properties, although it was presented as "particularly energizing, hypoglycemic, caffeine-based, and designed to reduce fatigue and improve performance.

OTHERNeutral ginger-flavored drink

A neutral ginger flavoured drink described as an energizing, hypoglycemic, caffeine-based drink, which is designed to reduce fatigue and improve performance.

OTHERNeutral ginger-flavored drink

A neutral ginger-flavored beverage bescribed as a mineral salt-based drink


Locations(1)

Don Gnocchi Foundation

Milan, Italy

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NCT06533137