RecruitingNCT06536725

Observation of Clinical Consistency of Organoid-chips Drug Sensitivity in Chemotherapy for PCa With Visceral Metastasis

Observation of Clinical Consistency of Organoid-on-chips Drug Sensitivity Detection in Chemotherapy for Prostate Cancer Patients With Visceral Metastasis


Sponsor

Tianjin Medical University Second Hospital

Enrollment

35 participants

Start Date

Jun 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This project plans to establish an organoid chip model of prostate cancer patients with internal organ metastasis from surgical or biopsy tissue sources, and test the sensitivity of commonly used chemotherapy drugs based on organoid chip drug sensitivity testing technology to screen out sensitive individualized treatment plans.


Eligibility

Sex: MALEMin Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study tests whether lab-grown "organoid chips" — tiny models built from a patient's own cancer cells — can accurately predict how prostate cancer with organ spread will respond to chemotherapy. If proven, this could help doctors personalize treatment plans. **You may be eligible if...** - You are 18 or older with prostate cancer that has spread to organs (visceral metastasis) - You are able to provide a surgical or biopsy tissue sample - Your liver, kidney, and bone marrow function meet minimum thresholds **You may NOT be eligible if...** - You have severe heart, liver, kidney, or autoimmune disease unrelated to cancer - A tissue sample cannot be obtained - You have active tuberculosis - You have had or are planned for an organ transplant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBuilding Organoid-on-chips models

This project obtains surgical or biopsy samples from prostate cancer patients with visceral metastasis for the construction of organoids.


Locations(2)

Tianjin Medical Unversity Second Hospital

Tianjin, Tianjin Municipality, China

Tianjin Medical Unversity Second Hospital

Tianjin, Tianjin Municipality, China

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NCT06536725


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