RecruitingNCT06542653

Effect of PCI on Clinical Prognosis of Chronic Coronary Artery Occlusion


Sponsor

The First Affiliated Hospital with Nanjing Medical University

Enrollment

258 participants

Start Date

Sep 17, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

Coronary chronic total occlusions (CTOs) are considered to increase the risk of adverse clinical outcomes. The purpose of this study was to evaluate whether long-term clinical outcomes could be improved by successful percutaneous coronary intervention (PCI) over optimal medical therapy (OMT) in CTO patients.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Inclusion Criteria1

  • patients with at least one coronary CTO lesion at our hospital in between January 2011 and December 2017

Exclusion Criteria4

  • (1) patients with ST-segment elevation myocardial infarction (STEMI)
  • (2)a history of coronary artery bypass grafting (CABG)
  • (3) cardiogenic shock
  • (4) malignant tumor. Patients were referred for PCI based on CTO-related symptoms or evidence of viability, or corresponding ischemia in the area of the CTO artery.

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Interventions

PROCEDUREPCI

successful percutaneous coronary intervention (PCI) in Coronary chronic total occlusions (CTOs) patients

DRUGOMT

optimal medical therapy (OMT) in CTO patients, such as aspirin 1td, ACEI/ARB 1td, β blocker 1td, statin 1td.


Locations(1)

The First Affiliated Hospital with Nanjing Medical University

Nanjing, Jiangsu, China

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NCT06542653


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