Tumor Antigen-sensitized DC Vaccine for Colorectal Cancer Liver Metastases

This study is testing a personalized cancer vaccine made from a patient's own tumor cells (dendritic cell vaccine) to help prevent colorectal cancer from coming back after surgery in patients who had their cancer removed and now show no evidence of disease. **You may be eligible if...** - You have confirmed colorectal cancer that has spread to the liver (stage IV) - Both the primary tumor and liver metastases have been completely removed - Your cancer tests as pMMR/MSS or MSI-Low (not the MSI-High subtype that responds to immunotherapy) - You have a high risk of recurrence (e.g., high liver metastasis risk score, or successful conversion therapy was needed) - Your main organ functions are normal **You may NOT be eligible if...** - You have an active HIV, Hepatitis B, or Hepatitis C infection - You have abnormal blood clotting - You have a mental health disorder - You have another active cancer Talk to your doctor to see if this trial is right for you.