RecruitingNCT06545981

Ocular Perfusion in Patients With Idiopathic Intracranial Hypertension


Sponsor

Medical University of Vienna

Enrollment

48 participants

Start Date

May 28, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

The proposed study aims to evaluate optic nerve head blood flow and microcirculation in patients with idiopathic intracranial hypertension. For this purpose, optic nerve head blood flow will be examined in patients with IIH before and after therapy and additionally compared with healthy age- and sex-matched control subjects. In addition, other parameters will be measured, in particular retinal blood flow, retinal oxygen saturation and retinal neurovascular coupling.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is measuring blood flow to the eye in people who have idiopathic intracranial hypertension (IIH) — a condition where pressure around the brain is too high for no clear reason, often causing headaches and vision problems — to better understand how this condition affects the eyes. **You may be eligible if...** - You are 18 or older and have been newly diagnosed with IIH, or are experiencing a relapse - You are a non-smoker - Healthy volunteers who are age- and sex-matched may also be eligible as a comparison group **You may NOT be eligible if...** - You have donated blood in the 3 weeks before the study - You are a smoker - You are pregnant or have recently given birth - You have other significant eye or medical conditions that could affect results Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERLumbar puncture and administration of medication

Patients with idiopathic intracranial hypertension will receive lumbar puncture and will be given medication to reduce intracranial pressure by neurologists. The lumbar puncture and the administration of medication are not part of this study, patients would also receive these without participating in the study.


Locations(1)

Medical University of Vienna

Vienna, Austria

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NCT06545981


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