Prostate Adaptive Radiation Therapy
Royal North Shore Hospital
130 participants
Oct 1, 2025
INTERVENTIONAL
Conditions
Summary
Prostate ART is a two phase study looking at using adaptive radiotherapy to help reduce toxicity for prostate cancer patients. Adaptive radiotherapy is a new technology that provides the ability to account for daily changes in anatomy. Adaptive radiotherapy also provides a foundation for which radiotherapy margins might be safely reduced. Phase 1 of this study is looking to see if a radiation therapist centred adaptive workflow can be implemented. If phase 1 of this study is safe and feasible, the study will proceed to phase 2. Part 2 of the study looks at using adaptive technology to reduce radiation treatment margins. The primary aim of this study is to see whether margin reduced treatment using adaptive radiotherapy can reduce side effects for prostate cancer patients.
Eligibility
Inclusion Criteria5
- \- Age \> 18
- Biopsy proven prostate malignancy
- Definitive treatment is radiotherapy to the prostate alone
- ECOG performance status 0-2
- Ability to understand and the willingness to sign an informed consent
Exclusion Criteria2
- Hip prosthesis
- Patient separation from prostate centre to skin edge \> 24cm, measured on diagnostic scan-
Interventions
Radiotherapy using adaptive technology to recontour and replan daily as required. Reductions in the PTV margin will also be introduced in the second phase of this study.
Standard radiation treatment used in the department of radiation oncology for prostate cancer
Locations(1)
View Full Details on ClinicalTrials.gov
For the most up-to-date information, visit the official listing.
NCT06547398