RecruitingNCT06547710

Primary Tumor Resection for M1a Stage Lung Cancer

Primary Tumor Resection for M1a Stage Lung Cancer With Occult Pleural Dissemination Discovered During Surgery: a Prospective, Single-arm, Multi-center, Phase Ⅱ Trial


Sponsor

Fudan University

Enrollment

66 participants

Start Date

Apr 1, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

This is a clinical trial from Eastern Cooperative Thoracic Oncology Project (ECTOP), numbered as ECTOP-1023. This study aims to explore the safety and efficacy of primary lesion resection in the treatment of M1a stage lung cancer with pleural dissemination found during surgery, and to more accurately evaluate whether primary lesion resection can improve the OS and quality of life of the corresponding patients.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This study is looking at whether surgically removing the primary (original) lung tumor in patients whose lung cancer has spread to the lining around the lung (called M1a stage) leads to better outcomes. In M1a lung cancer, tiny cancer cells are found on the pleura (the thin tissue lining the lungs) — and it is currently unclear whether removing the main tumor still helps patients. This trial aims to answer that question. **You may be eligible if...** - You are between 18 and 80 years old - You have been diagnosed with M1a stage lung cancer (cancer found on the pleural lining during or after surgery) - This is your first time receiving treatment for lung cancer — no prior surgery, chemotherapy, or radiation - Your lymph nodes were staged as cN0 before surgery (no apparent lymph node spread) - You are in good physical condition (ECOG score 0 or 1) **You may NOT be eligible if...** - The tumor cannot be fully removed surgically - You have a different type of lung malignancy (not lung cancer) - You have already had lung cancer surgery - You have already received radiation or chemotherapy for this cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Locations(1)

Fudan University Cancer Center

Shanghai, Shanghai Municipality, China

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NCT06547710


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