RecruitingNCT06548152

AQUALIS:QoL of CLL Patients Treated With Acalabrutinib in France, Retrospective Study Based on Data From PLATON Database

AQUALIS: Quality of Life of Patients With Chronic Lymphocytic Leukemia Treated With Acalabrutinib in France: a Retrospective Observational Study Based on Data Extracted From the PLATON Database


Sponsor

AstraZeneca

Enrollment

120 participants

Start Date

Apr 28, 2025

Study Type

OBSERVATIONAL

Conditions

Summary

QoL is often not assessed in real-world studies; hence, there is limited understanding about the real-world QoL of patients diagnosed with CLL. Besides, studies evaluating QoL have largely focused on comparing treated and untreated populations. In particular, QoL of patients treated with acalabrutinib has not been evaluated in a real-life setting. The aim of this study is to describe the QoL of CLL patients treated with acalabrutinib between the treatment initiation and twelve months after, in a real-life setting.


Eligibility

Inclusion Criteria6

  • The following patients will be eligible for inclusion in the AQUALIS study :
  • Patient enrolled in the PLATON database
  • Patient ≥18 years old
  • Treatment naïve CLL patient treated with acalabrutinib in a real life setting. Treatment pattern is Acala mono or Acala + Obinutuzumab
  • Patient who do not object to his health data collected in PLATON study being re-use for analysis/research purpose
  • Patients who started Acala but discontinued before 12 months are also included.

Exclusion Criteria4

  • Pregnant women
  • Patients under protection of justice
  • Patients over the age of 18 and unable to express their non-opposition
  • Patients with prior CLL treatments

Locations(1)

Research Site

Saint-Affrique, France

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NCT06548152


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