Longitudinal Study on Bacterial Production of LPC and LPA in Patients With Inflammatory Bowel Disease

This observational study is looking at the role of certain molecules (LPC and LPA) produced by gut bacteria in patients with inflammatory bowel disease (IBD) — either Crohn's disease or ulcerative colitis — who experience persistent abdominal pain even when their bowel inflammation appears controlled. The study aims to understand whether these bacterial molecules contribute to ongoing pain signals. **You may be eligible if...** - You are between 18 and 70 years old - You have been diagnosed with Crohn's disease or ulcerative colitis - You have a history of moderate to severe chronic abdominal pain that persists even when your inflammation is in remission or only mildly active - Your recent imaging and lab tests confirm low-level or no active inflammation **You may NOT be eligible if...** - Your IBD is currently in a severe active flare - You have other conditions that cause abdominal pain unrelated to IBD - You are pregnant - You have had recent bowel surgery - You do not meet the specific inflammation level thresholds defined by the study Talk to your doctor to see if this trial is right for you.