Cardiotoxicity of Carbon Monoxide in Patients Treated With Hyperbaric Oxygen Therapy
University Hospital, Brest
66 participants
Jul 25, 2022
OBSERVATIONAL
Conditions
Summary
Carbon monoxide poisoning is a frequent domestic accident and the leading cause of death from unintentionnal poisoning. Its toxicity is based on the CO binding to hemoglobin and myoglobin, inhibition of mitochondrial cytochrome oxidase, resulting in tissue hypoxia and reduced adenosine triphosphate synthesis and ischemia-reperfusion injury. This study aims to investigate the early and late cardiologic effects of CO in patients treated with hyperbaric oxygen (HBOT) for CO poisoning
Eligibility
Plain Language Summary
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NCT06549621