RecruitingNCT06549621

Cardiotoxicity of Carbon Monoxide in Patients Treated With Hyperbaric Oxygen Therapy


Sponsor

University Hospital, Brest

Enrollment

66 participants

Start Date

Jul 25, 2022

Study Type

OBSERVATIONAL

Conditions

Summary

Carbon monoxide poisoning is a frequent domestic accident and the leading cause of death from unintentionnal poisoning. Its toxicity is based on the CO binding to hemoglobin and myoglobin, inhibition of mitochondrial cytochrome oxidase, resulting in tissue hypoxia and reduced adenosine triphosphate synthesis and ischemia-reperfusion injury. This study aims to investigate the early and late cardiologic effects of CO in patients treated with hyperbaric oxygen (HBOT) for CO poisoning


Eligibility

Min Age: 18 YearsMax Age: 100 Years

Inclusion Criteria1

  • Patients treated for CO poisoning with HBOT in the hyperbaric and underwater medicine department of the Brest University hospital from 2015/01/01 to 2021/12/31

Exclusion Criteria1

  • refusal

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Locations(1)

CHRU de Brest

Brest, France

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NCT06549621


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