Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area
Exploratory Study of Consistency of Bi-Atrial Fibrosis Detected by Late Gadolinium Enhancement Magnetic Resonance Imaging and Low Voltage Area of Electroanatomic Mapping
China National Center for Cardiovascular Diseases
50 participants
Apr 1, 2024
OBSERVATIONAL
Conditions
Summary
This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2. To evaluate the electroanatomical characteristics of different types of fibrosis (dense fibrosis, patchy fibrosis, etc.) in different locations of the left and right atrium; 3. To explore the correlation between preoperative and postoperative bi-atrial fibrosis and long-term recurrence in patients with atrial fibrillation.
Eligibility
Inclusion Criteria2
- Adult patients (≥18 years old) who are willing to participate in this study and can sign informed consent;
- Atrial fibrillation was diagnosed and catheter ablation was proposed
Exclusion Criteria7
- Left atrial thrombus or left atrial appendage thrombus;
- Severe chronic obstructive pulmonary disease (FEV1/ FVC\<70%, FEV1\<50% predicted value);
- Absolute contraindications of anticoagulation therapy;
- Currently pregnant;
- Contraindications for LGE-MRI (claustrophobia, pacemaker implantation, eGFR\<30ml/min for renal insufficiency, severe obesity, pregnancy, gadolinium chelating agent allergy, etc.);
- refuse to participate in the study;
- other physical or mental incapacity to participate in the study.
Interventions
Participants will receive LGE-MRI scan before catheter ablation and 3 months after catheter ablation
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06552845