RecruitingNCT06552845

Consistency of LGE-MRI Fibrosis and EAM Low-voltage Area

Exploratory Study of Consistency of Bi-Atrial Fibrosis Detected by Late Gadolinium Enhancement Magnetic Resonance Imaging and Low Voltage Area of Electroanatomic Mapping

Sponsor

China National Center for Cardiovascular Diseases

Enrollment

50 participants

Start Date

Apr 1, 2024

Study Type

OBSERVATIONAL

Conditions

Atrial Fibrillation

Summary

This study aims to: 1. Assess the consistency of LGE-MRI bi-atrial fibrosis and electroanatomical mapping of bi-atrial low voltage region 2. To evaluate the electroanatomical characteristics of different types of fibrosis (dense fibrosis, patchy fibrosis, etc.) in different locations of the left and right atrium; 3. To explore the correlation between preoperative and postoperative bi-atrial fibrosis and long-term recurrence in patients with atrial fibrillation.

Eligibility

Min Age: 18 Years

Plain Language Summary

Simplified for easier understanding

This study is comparing two imaging methods used to map scar tissue in the heart of people with atrial fibrillation (an irregular heartbeat) — an MRI technique called LGE-MRI and a catheter-based electrical mapping technique — to see how well they agree with each other. Better scar mapping can help doctors plan more effective ablation procedures (where abnormal tissue is destroyed to restore a normal heart rhythm). **You may be eligible if...** - You are 18 or older - You have been diagnosed with atrial fibrillation - Your doctor has recommended a catheter ablation procedure **You may NOT be eligible if...** - You have a blood clot in the heart - You have severe COPD or cannot receive anticoagulation (blood thinners) - You have a pacemaker, are pregnant, have severe kidney disease (eGFR <30), severe obesity, or an allergy to MRI contrast dye - You refuse to participate Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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