The Impact of PReOPerative Exercise and NutritionaL Optimization on Perioperative Outcomes for Patients Undergoing Treatment for Rectal Cancer: The PROPEL Trial

This study is testing whether a program of preoperative exercise and nutritional optimization can improve recovery and outcomes for patients with stage II–III rectal cancer who are undergoing surgery after completing neoadjuvant treatment (chemotherapy and/or radiation given before surgery). **You may be eligible if...** - You are 18 or older with a diagnosed stage II or III rectal cancer - You are in the process of, or have just completed, neoadjuvant treatment (chemoradiation, total neoadjuvant therapy, or chemotherapy alone) - Your surgery is planned to follow - You speak English - You are currently doing less than 60 minutes of moderate-to-vigorous exercise per week **You may NOT be eligible if...** - Your cancer has already spread to other organs - You are physically unable to do exercise testing - You have health conditions that make exercise unsafe - You are being treated for a second cancer - You are already enrolled in another clinical trial with conflicting requirements Talk to your doctor to see if this trial is right for you.