RecruitingNot ApplicableNCT06569316

Genetic Testing for the Prevention of Cancer in Indigenous American Communities (JUNIPER Trial)

Journey to Understanding - Indigenous Peoples Engagement in Cancer Research Arizona (JUNIPER)


Sponsor

Mayo Clinic

Enrollment

300 participants

Start Date

Sep 27, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

This clinical trial is studying the genetic changes in cells associated with different types of cancer in Indigenous American (IA) populations in the Southwest to improve cancer screening, precision prevention, and therapeutic intervention for individual in these communities. IA tribes have much lower rates of cancer screening, have more limited access to healthcare, are more often diagnosed at later stages of disease, and have the poorest outcomes in all types of cancer when compared to any other racial and ethnic group in the United States. Due to these significant cancer health disparities, IAs have been understudied and little is known about the molecular characterization of tumors arising in IAs. Undergoing genetic testing of tumors may improve cancer outcomes in IA participants and communities.


Eligibility

Min Age: 18 Years

Inclusion Criteria3

  • Male or female adults >= 18 years of age
  • Cancer patient undergoing active treatment or a cancer survivor
  • Self-identify as Indigenous American

Exclusion Criteria3

  • Unable to provide informed consent
  • Individuals who are under 18 years of age
  • Prisoners

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Interventions

PROCEDUREBiospecimen Collection

Undergo blood or saliva and leftover tissue sample collection

OTHERCommunication Intervention

Receive care plan recommendations

OTHERGenetic Testing

Undergo genetic testing

OTHERSurvey Administration

Ancillary studies


Locations(1)

Mayo Clinic in Arizona

Scottsdale, Arizona, United States

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NCT06569316


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