RecruitingNCT06573853

Outcomes of PFA Vs. RFA for Patients with PSVT: a Retrospective and Propensity Score Matching Study

The Safety and Efficiency of Pulsed Field Ablation and Radiofrequency Ablation in the Treatment of Paroxysmal Supraventricular Tachycardia：a Retrospective and Propensity Score Matching Study

Sponsor

Caijie Shen

Enrollment

428 participants

Start Date

Oct 11, 2022

Study Type

OBSERVATIONAL

Conditions

Paroxysmal Supraventricular Tachycardia Catheter Ablation

Summary

The goal of this retrospective study is to compare the long-term follow-up outcomes of pulses field ablation (PFA) Vs. radiofrequency ablation (RFA) for the patients with paroxysmal supraventricular tachycardia (PSVT). The main question to answer is: Does the PFA was more effecient and safer that RFA for treatment of PSVT during procedure and after 1-year follow-up? Researchers will compare the acute and long-term efficiency and safety between PFA and RFA. 1. Recieved PFA or RFA 1 year ago 2. Finish the visit to the clinic at 1, 3, 6, 12 months for examinations and blood testings 3. Patients recieved PFA and PFA under propensity matched comparison according to differen variety of PSVT

Eligibility

Min Age: 18 YearsMax Age: 80 Years

Plain Language Summary

Simplified for easier understanding

This study compares two types of heart procedure for treating a rapid heart rhythm problem called paroxysmal supraventricular tachycardia (PSVT) — pulsed field ablation (PFA, which uses electrical pulses) versus radiofrequency ablation (RFA, which uses heat). It looks at which approach works better and causes fewer complications. **You may be eligible if...** - You are between 18 and 80 years old - You have symptomatic PSVT (specifically AVNRT or AVRT — types caused by short circuits in the heart's electrical system) - You are willing to undergo follow-up testing for one year **You may NOT be eligible if...** - You have structural heart disease (e.g., heart valve problems, congenital heart disease) - You have had previous heart surgery - You have had a prior failed ablation for PSVT - You have a pacemaker or other cardiac implant - You have an active infection or advanced cancer Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

PROCEDUREFocal Pulsed Field Ablation (PFA)

Patients in the PFA group underwent ablation procedures utilizing a force-sensing PFA catheter for the treatment of PSVT.

PROCEDUREFocal Radiofrequecy Ablation (RFA)

Patients in the PFA group underwent ablation procedures utilizing force-sensing RFA catheters for the treatment of PSVT.

Locations(1)

the First Affiliated Hospital of Ningbo University

Ningbo, Zhejiang, China

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NCT06573853

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