RecruitingNot ApplicableNCT06575140

Associative Peripheral Stimulation for Reduction of Motor Impairment During Acute Period of Stroke Recovery

Pilot Randomized Controlled Trial Assessing Associative Peripheral Stimulation (APS) for Reduction of Motor Impairment During Acute Period of Stroke Recovery


Sponsor

Ahmed A. Rahim

Enrollment

20 participants

Start Date

Dec 18, 2021

Study Type

INTERVENTIONAL

Conditions

Summary

Associative Peripheral Stimulation (APS) is a non-invasive therapy intended for stroke rehabilitation involving transcutaneous electrical muscle stimulation paired with voluntary movement. This pilot study investigates whether APS applied during the acute phase of stroke recovery may reduce impairment and improve function in the affected upper extremity.


Eligibility

Min Age: 18 YearsMax Age: 79 Years

Inclusion Criteria5

  • Confirmed ischemic or hemorrhagic stroke no earlier than 7 days prior to enrollment;
  • Presentation of hemiparesis or paralysis of the upper extremity due to stroke;
  • Ability to comprehend and follow study instructions;
  • Ability to initiate finger extension (≥3°) at least three times per minute;
  • Fugl-Meyer Assessment (Upper Extremity) score of <47.

Exclusion Criteria5

  • Contraindications, intolerance, or high sensitivity to the experimental protocol;
  • History of upper-extremity disability prior to the index stroke;
  • Neurological conditions (other than stroke) affecting motor function;
  • Treatment of spasticity/increased tone in the affected upper extremity (e.g., with Botox injection);
  • Lack of access to a safe and suitable place of discharge for experimental sessions and follow-up visits.

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Interventions

DEVICEAssociative Peripheral Stimulation (APS) 1.0

Associative peripheral stimulation paired with rehabilitative exercises.

DEVICEPeripheral Neuromuscular Stimulation

Random peripheral stimulation paired with rehabilitative exercises.


Locations(3)

General Hospital of Mexico

Mexico City, Mexico

La Raza National Medical Center

Mexico City, Mexico

National Institute of Neurology & Neurosurgery

Mexico City, Mexico

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NCT06575140


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