Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Pain, Anxiety and Depression in Patients With Resectable Head and Neck Squamous Cell Carcinoma

This study measures how pre-surgery chemotherapy combined with immunotherapy (anti-PD-1 drugs) affects pain, anxiety, and depression in patients with resectable head and neck squamous cell carcinoma. It tracks psychological well-being alongside cancer treatment. **You may be eligible if...** - You have been diagnosed with head and neck squamous cell carcinoma (stage I–IVA) and have not yet received any treatment - You are planning to have surgery, possibly combined with chemotherapy and immunotherapy - You can speak Chinese and have basic reading and writing skills **You may NOT be eligible if...** - You have dementia or delirium - You consume alcohol heavily (more than 4 times per day or more than 4 times per week) - You are currently taking or have previously taken antidepressants - You change your treatment plan during the study Talk to your doctor to see if this trial is right for you.