RecruitingNot ApplicableNCT06575712

Coping Skills Training for Symptom Management and Daily Steps (Step Up)


Sponsor

Duke University

Enrollment

177 participants

Start Date

Apr 21, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The aim of this study is to test the efficacy of a hybrid in-person and mHealth coping skills training and activity coaching intervention (Step Up), to enable HCT patients to effectively cope with symptoms (pain, fatigue, and stress) to improve their ability to engage in physical activity that can improve physical disability.


Eligibility

Min Age: 18 YearsMax Age: 99 Years

Inclusion Criteria4

  • receipt of an autologous (auto) HCT or CAR-T cell therapy due to a hematologic malignancy, such as a diagnosis of leukemia, lymphoma, multiple myeloma
  • age \>18
  • self-reported fatigue, pain, and psychological distress (confirmed at recruitment) - minimum two of three symptoms reported at \>3 on 0-10 scale
  • life expectancy \> 12 months

Exclusion Criteria4

  • cognitive impairment (e.g., dementia) recorded in the chart or suspected by provider
  • metastases to the brain
  • presence of a severe psychiatric condition (e.g., psychotic disorder) that would contraindicate safe participation as indicated by the medical chart, treating oncologist, or interactions with the medical/study staff
  • inability to converse in English

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Interventions

BEHAVIORALStep Up

A hybrid in-person and mHealth (mobile health) coping skills training and activity coaching intervention.

OTHERUsual Care Plus (UC+)

Usual medical care plus videos delivering educational content via an app.


Locations(1)

Duke Cancer Institute

Durham, North Carolina, United States

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NCT06575712


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