Effects of Neoadjuvant Therapy With Carboplatin, Paclitaxel Combined With Anti-PD-1 Drugs on Cognitive Function in Patients With Resectable Head and Neck Squamous Cell Carcinoma

This study is examining how chemotherapy and immunotherapy before surgery for head and neck cancer affects thinking and memory (cognitive function) in patients in China. Researchers want to understand if these treatments cause any mental fog or thinking changes. **You may be eligible if...** - You have been diagnosed with head and neck squamous cell carcinoma (stage I–IVA) and have not yet received treatment - You are planned for surgery, with or without chemotherapy and immunotherapy - You can speak Chinese and have basic reading/writing ability **You may NOT be eligible if...** - You have a brain tumor, brain injury, or any neurological condition - You have previously had a different type of cancer (other than skin cancer) - You have serious psychiatric illness - You are unable to cooperate with cognitive testing Talk to your doctor to see if this trial is right for you.