RecruitingPhase 1Phase 2NCT06581419

A Clinical Trial to Evaluate Effect of IAP0971 in Patients With Advanced Malignant Tumors

A Phase I/II Clinical Study Evaluating Safety, Tolerability, and Efficacy of IAP0971 in Advanced Tumors


Sponsor

SUNHO(China)BioPharmaceutical CO., Ltd.

Enrollment

78 participants

Start Date

Dec 31, 2024

Study Type

INTERVENTIONAL

Conditions

Summary

Phase I: To evaluate the safety, tolerance and effectiveness of IAP0971 for the treatment of advanced malignant tumors. Phase II: Evaluation of IAP0971 therapy driver negative and PD-L1 positive (TPS≥50%) The initial treatment is effective in subjects with advanced or metastatic non-small cell lung cancer.


Eligibility

Min Age: 18 YearsMax Age: 75 Years

Plain Language Summary

Simplified for easier understanding

This early-phase trial tests a new investigational drug called IAP0971 in people with advanced solid tumors or blood cancers that have not responded to standard treatments. The study first tests safety and finds the right dose, then expands to test effectiveness in specific cancer types. **You may be eligible if...** - You are between 18 and 75 years old - You have advanced solid tumor cancer or certain blood cancers confirmed by biopsy - Your cancer has not responded to standard treatments, or no standard treatment is available - You are in reasonably good overall health (able to care for yourself) **You may NOT be eligible if...** - You have active brain metastases (cancer spread to the brain) - You have had major surgery or radiotherapy recently without adequate recovery - You have serious heart, liver, or kidney problems Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

DRUGIAP0971

Subjects receive IAP0971, which will be administered every 3 weeks in a 3-week cycle.


Locations(1)

Cancer Hospital Chinese Academy of Medical Sciences

Beijing, Beijing Municipality, China

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NCT06581419


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