RecruitingNot ApplicableNCT06582316

Digital Solution for Salutogenic Brain Health (DiSaB): A Pilot Protocol for Clinical Implementation

Digital Solution for Salutogenic Brain Health (DiSaB): A Pilot Sequential Multiple Assignment Randomised Trial (SMART) Protocol for Clinical Implementation


Sponsor

National University of Singapore

Enrollment

160 participants

Start Date

Apr 2, 2025

Study Type

INTERVENTIONAL

Conditions

Summary

The goal of this clinical trial is to develop and learn if a digitally delivered brain health intervention (DiSaB) can help improve cognitive, physical and psychosocial health in middle-aged adults with chronic conditions at-risk for cognitive decline. The clinical trial also aims to find out the push and pull factors of implementing the intervention in primary care settings. The main questions it aims to answer are: 1. Does the DiSaB intervention improve participants' cognitive functions, health measures, and psychosocial health? 2. Is an individualised or group-based health education session better at improving cognitive, physical and psychosocial health in participants who did not respond to the DiSaB intervention? 3. How useful and practical is the DiSaB intervention, according to 1. participants and 2. nurses carrying out the intervention? The investigators will compare a DiSaB intervention to a control condition (where participants do not undergo any intervention) to see if the DiSaB intervention works in improving participants' health. The investigators will also compare individualised versus group health education sessions to see which session is better at improving the health of participants who did not respond to the DiSaB intervention. Participants will 1. Complete cognitive assessments, questionnaires, and health tests before intervention, immediately after the intervention, and 6 months after the intervention 2. Either undergo no intervention, or undergo the DiSaB intervention over 2 months 3. Be randomly selected to attend focus group interviews Local champions will complete questionnaires and attend focus group interviews after administering and/or co-facilitating the intervention.


Eligibility

Min Age: 40 YearsMax Age: 64 Years

Plain Language Summary

Simplified for easier understanding

This pilot study tests a digital health program designed to reduce the risk of dementia and support brain health in middle-aged adults who have chronic health conditions like high blood pressure, high cholesterol, or type 2 diabetes. The program targets lifestyle factors — such as sleep, diet, and exercise — that affect brain health. **You may be eligible if...** - You are between 40 and 55 years old - You have high blood pressure, high cholesterol, or type 2 diabetes - You can read, write, and speak English - You are able to provide written informed consent **You may NOT be eligible if...** - You have a life-threatening condition with a life expectancy of less than one year - Your overall risk score does not meet the study threshold (assessed at screening) - You already have significant cognitive impairment or dementia Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

OTHERBrain Health Training Programme

"Train Your Brain (TYB)" - group-based cognitive intervention programme for mild cognitive impairments. This programme equips participants with knowledge on cognition and brain health, provide cognitive coping strategies and boost their confidence and maintain independence in daily activities.


Locations(1)

National University Polyclinics

Singapore, Singapore

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NCT06582316


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