Remifentanil and Remimazolam to Limit Patient Movement
Remifentanil and Remimazolam to Limit Patient Movement During Long-Eye Surgeries Under Local Anesthesia
Egymedicalpedia
70 participants
Jul 10, 2024
INTERVENTIONAL
Conditions
Summary
Local anesthetics (LA) may be administered by injection (retrobulbar, peribulbar, subconjunctival, lid, or facial block) or by instillation (topical anesthesia), Considerable drawbacks of local anesthesia in these patients include the fact that a few patients can remain comfortable on an operating table for procedures that exceed two or three hours. Sedation may be helpful with LA to decrease the experience of discomfort, movement and anxiety, which may in turn positively influence hemodynamic parameters, patient satisfaction, and overall improve surgical safety. Sedatives used in eye surgeries include benzodiazepines, opioids, alpha-adrenoceptor agonists, and propofol.
Eligibility
Inclusion Criteria4
- Age > 40 years.
- Both sexes.
- American Society of Anesthesiology (ASA) physical status I-III.
- Undergoing long-eye surgeries under local anesthesia using peribulbar block with an expected surgical time of more than one hour.
Exclusion Criteria10
- Patients on aspirin or anticoagulants.
- Allergy to any study medication.
- Drug abuse.
- Uncontrolled hypertension.
- Hyperthyroidism.
- Frequent cough.
- Impaired hearing.
- Severe liver and kidney dysfunction.
- Neurological or psychological disorders.
- Partial or failed block.
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Interventions
to compare remifentanil and remimazolam to limit patient movement during long-eye surgeries under local anesthesia.
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06583811