RecruitingNCT06584097

COMparative Performance of General Purpose Models

COMparative Performance of General Purpose Models for Propofol And REmifentanil in Neurosurgical Patients Admitted to the Intensive Care Unit


Sponsor

Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta

Enrollment

42 participants

Start Date

Oct 2, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

To compare the performance of the Eleveld models for propofol and remifentanil on neurosurgery patients admitted to intensive care with their intraoperative performance.


Eligibility

Inclusion Criteria1

  • Adult patients undergoing elective neurosurgical procedures with an expected sedation after surgery of > 12 hours • Requirement for an arterial line

Exclusion Criteria6

  • Pregnancy
  • Known sensitivity or allergy to propofol or remifentanil
  • Patient participating in research for which a period of exclusion is currently required by other study protocol, ethical committee or health authority.
  • Age < 18 years old
  • Patients subjected to infusion of propofol and/or remifentanil not delivered through TCI pumps before the inclusion
  • Patients exposed to other sedatives (benzodiazepines, volatile anesthetics, quetiapine) before the inclusion

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Locations(2)

Foundation IRCCS Carlo Besta Neurological Institute

Milan, Italy, Italy

Fondazione IRCCS Istituto Neurologico C. Besta

Milan, Milano, Italy

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NCT06584097