RecruitingNot ApplicableNCT06586164

Enhancing Rehabilitation for Veterans With Serious Mental Illness

Enhancing Rehabilitation for Veterans With Serious Mental Illness Via Biomarker-Informed Cognitive Training

Sponsor

VA Office of Research and Development

Enrollment

80 participants

Start Date

Feb 25, 2025

Study Type

INTERVENTIONAL

Conditions

Schizophrenia PTSD Bipolar Disorder Psychosis Schizoaffective Disorder Serious Mental Illness

Summary

This study addresses the critical need for innovative therapeutic interventions in Veterans with serious mental illnesses (SMI) receiving care in VA Psychosocial Rehabilitation and Recovery Centers (PRRCs). The vast majority of individuals with SMI suffer from cognitive impairments, leading to chronic functional disability, and impaired outcomes, causing a significant strain on support networks and the VA healthcare system. This study aims to introduce an innovative mental health therapy, Targeted Cognitive Training (TCT), to Veterans struggling with serious mental illnesses (SMI). TCT works to improve basic sensory information processing and, ultimately, clinical, cognitive, and psychosocial functioning. By using EEG biomarkers to identify Veterans with SMI receiving care within VA Psychosocial Rehabilitation and Recovery Centers who are most likely to benefit from this treatment, and by understanding how best to implement this therapy, the investigators hope to enhance care and improve life quality for Veterans with SMI.

Eligibility

Min Age: 18 YearsMax Age: 83 Years

Plain Language Summary

Simplified for easier understanding

This study is testing a new rehabilitation program designed to enhance cognitive and functional recovery for veterans living with serious mental illness (such as schizophrenia, bipolar disorder, or PTSD) who are participating in psychiatric rehabilitation programs. **You may be eligible if...** - You are a veteran between 18 and 83 years old - You have a serious mental illness (such as schizophrenia, schizoaffective disorder, bipolar disorder, or PTSD) - You are currently enrolled in psychiatric rehabilitation services - You can hear tones at a standard volume and see with at least 20/40 vision (corrected) - You can speak and read English fluently **You may NOT be eligible if...** - You are not a veteran - You have significant hearing or vision problems that cannot be corrected - You have a neurological condition (such as a recent stroke or brain injury) that would interfere with the study - You are unable to participate in the testing or program requirements Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

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Interventions

BEHAVIORALTargeted Cognitive Training

TCT is a computer-based cognitive training program in which participants train on progressively more difficult auditory processing exercises in order to improve speed, accuracy and fidelity of auditory information processing in order to generate gains in cognition and functioning.

Locations(1)

VA San Diego Healthcare System, San Diego, CA

San Diego, California, United States

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NCT06586164

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