Anti-CD70-CAR-T Cell Injection for the Treatment of Locally Advanced or Relapsed/Metastatic CD70+ Inoperable Renal Cells

This study is testing a CAR-T cell therapy (a treatment where your own immune cells are engineered in a lab to attack cancer cells expressing a protein called CD70) in patients with advanced kidney cancer (renal cell carcinoma) that has not responded to prior treatments. **You may be eligible if...** - You are between 18 and 70 years old - You have advanced malignant kidney cancer (renal cell carcinoma) confirmed by biopsy or cell testing - Your tumor cells are confirmed to be CD70-positive - You have already received at least one VEGFR-targeted therapy AND an immune checkpoint therapy - Your overall health and organ function meet the study requirements **You may NOT be eligible if...** - You have uncontrolled active infections - You have autoimmune diseases requiring systemic treatment - You have severe heart, liver, or kidney dysfunction - You are pregnant or breastfeeding - You have active brain metastases Talk to your doctor to see if this trial is right for you.