RecruitingNCT06587906

Postoperative Complications Following Skull Base Tumor Resection

Postoperative Complications Following Skull Base Tumor Resection: an Observational Study

Sponsor

Beijing Tiantan Hospital

Enrollment

122 participants

Start Date

Sep 10, 2024

Study Type

OBSERVATIONAL

Conditions

Postoperative Complications Skull Base Tumor

Summary

The skull base tumor is located in the deep intracranial layer and is closely related to the brain stem and intracranial nerves. The incidence of postoperative complications after skull base tumor resection is high. Therefore, the perioperative management of skull base tumor resection is challenging.

Eligibility

Min Age: 18 Years

Inclusion Criteria4

Age 18 and above
American Society of Anesthesiologists physical status I to III
Undergoing elective resection of skull base tumors
Obtaining written informed consent

Exclusion Criteria7

Heart failure, myocarditis, pericarditis, and cardiomyopathy
Myocardial ischemia less than 6 months old
Severe arrhythmia
Severe bradycardia (heart rate below 50 beats per minute)
Unable to complete preoperative cardiac assessment
Severe liver dysfunction (Child Pugh C-grade)
Severe lung diseases

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Interventions

OTHERPulmonary ultrasound examination

All ultrasound scans were performed by the same anaesthetists. Pulmonary ultrasound examination was performed at two time points for each patient: 20 min before starting mechanical ventilation of the lungs when patients were placed in the supine position(preoperative), 20 min after after surgery end at the time the patient was placed in the supine position (postoperative), before Intubation and after extubation Patientswere scanned in the supine position following the pulmonary ultrasound examination method The thorax was divided by the anterior axillary line, the posterior axillary line, and a horizontal line beneath nipple. Twelve intercostal spaces of each area were scanned and analysed. Aeration loss was assessedby calculating the modified LUS score that is calculated mainly using the amount of B-line The pulmonary ultrasound score of the hemithorax (0-18).