Individualized Exploration of Aerobic Exercise-assisted Treatment of Depression

This study is exploring whether personalized aerobic exercise programs can boost the effectiveness of antidepressant treatment for people with clinical depression. **You may be eligible if...** - You are between 18 and 45 years old - You have been diagnosed with a depressive disorder according to DSM-5 criteria - Your depression score indicates moderate to severe symptoms (HAMD-17 score of 14 or above) - You are either currently on antidepressants for at least 4 weeks, or not taking antidepressants - You do not have bipolar disorder (screened out by questionnaire) **You may NOT be eligible if...** - You have another mental health diagnosis (schizophrenia, bipolar disorder, eating disorder, substance abuse) - You have a neurological condition such as stroke, epilepsy, Parkinson's disease, or brain tumor - You have heart disease or high blood pressure that makes exercise risky - You are currently in structured psychological therapy - You are physically unable to exercise (e.g., physical disability or injury) Talk to your doctor to see if this trial is right for you.