RecruitingNCT06594861

Follow-up Study of Individuals with Autoantibodies Against Ro/SSA and La/SSB

Follow-up of Clinical Manifestations and Inflammation-related Parameters in Individuals with Autoantibodies Against Ro/SSA and La/SSB


Sponsor

Karolinska Institutet

Enrollment

500 participants

Start Date

Feb 9, 2024

Study Type

OBSERVATIONAL

Conditions

Summary

In this study, individuals with autoantibodies against Ro/SSA and La/SSB will be followed with regard to clinical manifestations and immunological parameters to identify immunological changes, environmental factors, and early clinical symptoms that characterize the progression from serological autoreactivity to clinically manifest disease.


Eligibility

Min Age: 18 Years

Inclusion Criteria4

  • To be included in the risk group, the following criteria must be met:
  • \- At least one instance of testing positive for Ro/SSA or La/SSB, regardless of the method used.
  • To be included in the control group, the individual must:
  • \- Have no rheumatologic disease and no autoantibodies against Ro/SSA or La/SSB.

Exclusion Criteria4

  • Below 18 years of age
  • Inability to consent to their own participation
  • Ongoing infection or severe illness where the study physician deems participation in the study not to be in the individuals best interest
  • Inability to read and understand Swedish, and therefore unable to complete the forms and questionnaires included in the project

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Interventions

OTHERNo intervention

No intervention.


Locations(1)

Centrum för reumatologi

Stockholm, Sweden

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NCT06594861


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