4-Aminopyridine to Treat Skin Burns
John Elfar
200 participants
Jan 1, 2026
INTERVENTIONAL
Conditions
Summary
Many patients suffer from traumatic burns and current treatments do not increase the regenerative potential of either skin grafts or the remaining uninjured skin. There is a need to develop treatments to accelerate and improve healing of burn injuries. More research is needed to evaluate the role of 4-AP, a promising new agent with an excellent safety profile, on wound and burn healing. The investigational treatment will be used to test the hypothesis that 4-AP accelerates burn healing in traumatically burned patients.
Eligibility
Plain Language Summary
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Interventions
Active study drug
Placebo comparator
Locations(1)
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NCT06596434