Cardiac Assessment and Takotsubo-stunning Among COPD-exacerbations In-Hospital
Prospective Observational Study of Myocardial Stunning in Patients Hospitalized for Exacerbation of Chronic Obstructive Pulmonary Disease
Sahlgrenska University Hospital
200 participants
Sep 23, 2024
OBSERVATIONAL
Conditions
Summary
The goal of this prospective observational study is to investigate to what extent acute exacerbation of chronic obstructive pulmonary disease (AE-COPD) triggers Takotsubo-stunning, and how this affects the outcome for these patients. The main questions it aims to answer are: 1. What is cumulative incidence of Takotsubo-stunning in patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S (Gothenburg, Sweden)? 2. Among patients hospitalized for AE-COPD at Sahlgrenska University Hospital/S, what is the risk of in-hospital clinical manifestations of acute heart failure in patients with Takotsubo-stunning compared to those without?
Eligibility
Inclusion Criteria3
- Adult patients (≥ 18 years old) admitted to hospital ward for AE-COPD
- Inclusion within 72 hours of admission,
- Written informed consent
Exclusion Criteria2
- Prior acute myocardial infarction or known pre-existing persistent regional wall motion abnormality or left ventricular dysfunction (left ventricular ejection fraction \[LVEF\] \<50%)
- Expected inability to comply with the protocol (e.g. dementia)
Locations(1)
View Full Details on ClinicalTrials.gov
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NCT06597331