RecruitingNCT06599424

IntraRenal HEmoDynamics to IntegraTE CA-AKI Risk and Monitor NephroprotectiIoN by ImpElla Support.


Sponsor

Heinrich-Heine University, Duesseldorf

Enrollment

550 participants

Start Date

Oct 1, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

the hypothesis is that elevation of the intrarenal resistive index (RI) characterizes patients at elevated risk for subsequent CA-AKI and integrates items of the Mehran AKI risk score into a single, readily obtainable parameter. Impella-mediated nephroprotection confers to reduction of elevated RI by restoration of intrarenal venous flow profile.


Eligibility

Min Age: 18 YearsMax Age: 90 Years

Plain Language Summary

Simplified for easier understanding

This study is examining whether monitoring blood flow inside the kidneys during a heart procedure called PCI (a procedure to open blocked heart arteries) can help predict and prevent kidney injury — a known complication that can occur after using contrast dye during the procedure. A heart-assist device called Impella may be used during the procedure. **You may be eligible if...** - You are between 18 and 90 years old - You are scheduled to have a PCI (coronary artery stenting procedure) in the near future or on the same day **You may NOT be eligible if...** - You have severe chronic kidney disease (very low kidney function) or are on dialysis - You have had a recent kidney injury in the past week - You are having a STEMI heart attack (a type of severe heart attack) within the last 24 hours, or have complications from a heart attack - You are in cardiogenic shock (heart not pumping enough to maintain blood pressure) - You had a cardiac arrest during this hospital stay and haven't fully recovered - You have a very low platelet count or active bleeding - You are pregnant or may be pregnant Talk to your doctor to see if this trial is right for you.

This summary was AI-generated to explain the trial in plain language. It is not medical advice. Always discuss eligibility with your doctor before enrolling in a clinical trial.

Interested in this trial?

Get notified about updates and connect with the research team.

Interventions

OTHERObservational

Observational


Locations(2)

Department of Cardiology, Angiology and Intensive Care Medicine Campus at German Heart Center Charite

Berlin, Germany

Division of Cardiology, Pulmonary Disease and Vascular Medicine at University Hospital Duesseldorf

Düsseldorf, Germany

View Full Details on ClinicalTrials.gov

For the most up-to-date information, visit the official listing.

Visit

NCT06599424


Related Trials