RecruitingNCT06600659

A Study to Determine Number of Patients Who Develop High Ammonia Levels After Receiving Recombinant Erwinia Asparaginase

A Pilot Study to Establish Incidence and Characteristics of Patients at Risk for Symptomatic Hyperammonemia Secondary to Recombinant Erwinia Asparaginase


Sponsor

Mayo Clinic

Enrollment

10 participants

Start Date

Nov 2, 2023

Study Type

OBSERVATIONAL

Conditions

Summary

This study evaluates the incidence of symptomatic hyperammonemia (high ammonia levels) in patients being treated with recombinant Erwinia asparaginase.


Eligibility

Min Age: 1 Year

Inclusion Criteria2

  • Followed by pediatric hematology/oncology
  • Receiving recombinant Erwinia asparaginase for treatment of malignancy

Exclusion Criteria2

  • Patients \< 1 year of age
  • Patients who have previously received recombinant Erwinia asparaginase within the past two weeks

Interventions

OTHERNon-Interventional Study

Non-interventional study


Locations(1)

Mayo Clinic in Rochester

Rochester, Minnesota, United States

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NCT06600659


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